Researchers contend that atherosclerotic cardiovascular disease and the moderate inflammation brought on by H pylori infection. Some research, meanwhile, were unable to support this association. Uncertainty still exists regarding the underlying mechanism by which H pylori infection encourages the growth of cardiovascular disease. Major risk factors for heart disease include changes in blood cholesterol levels, such as higher low-density lipoprotein and decreased high-density lipoprotein. After cholesterol, people could experience heartburn and GERD. Typically, cholesterol symptoms do not appear until the issue is severe. In those circumstances, fat builds up on the skin and contributes to digestive issues like acid reflux, heartburn, GERD, and stomach pain. This condition that affects the gallbladder is called cholesterolosis. A tiny pear-shaped structure under the liver is the gallbladder. In order to aid in food digestion, the gallbladder converts cholesterol and lipids into cholesteryl esters and stores bile. Fatty acids can be transferred from the body to the circulation thanks to these cholesteryl esters. When cholesteryl esters accumulate, cholesterololosis results. These create polyps by adhering to the gallbladder's walls.

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